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1.

Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.

Zhou, Panpan; Song, Ge; Liu, Hejun; Yuan, Meng; He, Wan-Ting; Beutler, Nathan; Zhu, Xueyong; Tse, Longping V; Martinez, David R; Schäfer, Alexandra; Anzanello, Fabio; Yong, Peter; Peng, Linghang; Dueker, Katharina; Musharrafieh, Rami; Callaghan, Sean; Capozzola, Tazio; Limbo, Oliver; Parren, Mara; Garcia, Elijah; Rawlings, Stephen A; Smith, Davey M; Nemazee, David; Jardine, Joseph G; Safonova, Yana; Briney, Bryan; Rogers, Thomas F; Wilson, Ian A; Baric, Ralph S; Gralinski, Lisa E; Burton, Dennis R; Andrabi, Raiees.

Immunity; 56(3): 669-686.e7, 2023 03 14.

Artículo en Inglés | MEDLINE | ID: mdl-36889306

2.

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies.

Briney, Bryan; Sok, Devin; Jardine, Joseph G; Kulp, Daniel W; Skog, Patrick; Menis, Sergey; Jacak, Ronald; Kalyuzhniy, Oleksandr; de Val, Natalia; Sesterhenn, Fabian; Le, Khoa M; Ramos, Alejandra; Jones, Meaghan; Saye-Francisco, Karen L; Blane, Tanya R; Spencer, Skye; Georgeson, Erik; Hu, Xiaozhen; Ozorowski, Gabriel; Adachi, Yumiko; Kubitz, Michael; Sarkar, Anita; Wilson, Ian A; Ward, Andrew B; Nemazee, David; Burton, Dennis R; Schief, William R.

Cell; 166(6): 1459-1470.e11, 2016 Sep 08.

Artículo en Inglés | MEDLINE | ID: mdl-27610570

3.

PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.

Gavin, Amanda L; Huang, Deli; Huber, Christoph; Mårtensson, Annica; Tardif, Virginie; Skog, Patrick D; Blane, Tanya R; Thinnes, Therese C; Osborn, Kent; Chong, Hayley S; Kargaran, Farnaz; Kimm, Phoebe; Zeitjian, Armen; Sielski, Rachel L; Briggs, Megan; Schulz, Sebastian R; Zarpellon, Alessandro; Cravatt, Benjamin; Pang, Ee Shan; Teijaro, John; de la Torre, Juan Carlos; O'Keeffe, Meredith; Hochrein, Hubertus; Damme, Markus; Teyton, Luc; Lawson, Brian R; Nemazee, David.

Nat Immunol; 19(9): 942-953, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30111894

4.

The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity.

Gonzalez-Martin, Alicia; Adams, Brian D; Lai, Maoyi; Shepherd, Jovan; Salvador-Bernaldez, Maria; Salvador, Jesus M; Lu, Jun; Nemazee, David; Xiao, Changchun.

Nat Immunol; 17(4): 433-40, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26901150

5.

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens.

Abbott, Robert K; Lee, Jeong Hyun; Menis, Sergey; Skog, Patrick; Rossi, Meghan; Ota, Takayuki; Kulp, Daniel W; Bhullar, Deepika; Kalyuzhniy, Oleksandr; Havenar-Daughton, Colin; Schief, William R; Nemazee, David; Crotty, Shane.

Immunity; 48(1): 133-146.e6, 2018 01 16.

Artículo en Inglés | MEDLINE | ID: mdl-29287996

6.

A broad and potent neutralization epitope in SARS-related coronaviruses.

Yuan, Meng; Zhu, Xueyong; He, Wan-Ting; Zhou, Panpan; Kaku, Chengzi I; Capozzola, Tazio; Zhu, Connie Y; Yu, Xinye; Liu, Hejun; Yu, Wenli; Hua, Yuanzi; Tien, Henry; Peng, Linghang; Song, Ge; Cottrell, Christopher A; Schief, William R; Nemazee, David; Walker, Laura M; Andrabi, Raiees; Burton, Dennis R; Wilson, Ian A.

Proc Natl Acad Sci U S A; 119(29): e2205784119, 2022 07 19.

Artículo en Inglés | MEDLINE | ID: mdl-35767670

7.

The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow.

Siggs, Owen M; Arnold, Carrie N; Huber, Christoph; Pirie, Elaine; Xia, Yu; Lin, Pei; Nemazee, David; Beutler, Bruce.

Nat Immunol; 12(5): 434-40, 2011 May.

Artículo en Inglés | MEDLINE | ID: mdl-21423172

8.

A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs.

Huang, Deli; Tran, Jenny Tuyet; Peng, Linghang; Yang, Linlin; Suhandynata, Raymond T; Hoffman, Melissa A; Zhao, Fangzhu; Song, Ge; He, Wan-Ting; Limbo, Oliver; Callaghan, Sean; Landais, Elise; Andrabi, Raiees; Sok, Devin; Jardine, Joseph G; Burton, Dennis R; Voss, James E; Fitzgerald, Robert L; Nemazee, David.

J Immunol; 207(1): 344-351, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-34183368

9.

B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.

Huang, Deli; Abbott, Robert K; Havenar-Daughton, Colin; Skog, Patrick D; Al-Kolla, Rita; Groschel, Bettina; Blane, Tanya R; Menis, Sergey; Tran, Jenny Tuyet; Thinnes, Theresa C; Volpi, Sabrina A; Liguori, Alessia; Schiffner, Torben; Villegas, Sophia M; Kalyuzhniy, Oleksandr; Pintea, Mark; Voss, James E; Phelps, Nicole; Tingle, Ryan; Rodriguez, Alberto R; Martin, Greg; Kupryianov, Sergey; deCamp, Allan; Schief, William R; Nemazee, David; Crotty, Shane.

Proc Natl Acad Sci U S A; 117(37): 22920-22931, 2020 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-32873644

10.

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.

Wu, Nicholas C; Yuan, Meng; Bangaru, Sandhya; Huang, Deli; Zhu, Xueyong; Lee, Chang-Chun D; Turner, Hannah L; Peng, Linghang; Yang, Linlin; Burton, Dennis R; Nemazee, David; Ward, Andrew B; Wilson, Ian A.

PLoS Pathog; 16(12): e1009089, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33275640

11.

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.

Antanasijevic, Aleksandar; Ueda, George; Brouwer, Philip J M; Copps, Jeffrey; Huang, Deli; Allen, Joel D; Cottrell, Christopher A; Yasmeen, Anila; Sewall, Leigh M; Bontjer, Ilja; Ketas, Thomas J; Turner, Hannah L; Berndsen, Zachary T; Montefiori, David C; Klasse, Per Johan; Crispin, Max; Nemazee, David; Moore, John P; Sanders, Rogier W; King, Neil P; Baker, David; Ward, Andrew B.

PLoS Pathog; 16(8): e1008665, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32780770

12.

MicroRNA control of B cell tolerance, autoimmunity and cancer.

Xiao, Changchun; Nemazee, David; Gonzalez-Martin, Alicia.

Semin Cancer Biol; 64: 102-107, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32522353

13.

Commercial Serology Assays Predict Neutralization Activity against SARS-CoV-2.

Suhandynata, Raymond T; Hoffman, Melissa A; Huang, Deli; Tran, Jenny T; Kelner, Michael J; Reed, Sharon L; McLawhon, Ronald W; Voss, James E; Nemazee, David; Fitzgerald, Robert L.

Clin Chem; 67(2): 404-414, 2021 01 30.

Artículo en Inglés | MEDLINE | ID: mdl-33084854

14.

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells.

Sinha, Ranjeet K; Flynn, Ryan; Zaiken, Michael; Paz, Katelyn; Gavin, Amanda L; Nemazee, David; Fernández, José A; Xu, Xiao; Griffin, John H; Blazar, Bruce R.

Blood; 134(9): 776-781, 2019 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-31243040

15.

B Cells Carrying Antigen Receptors Against Microbes as Tools for Vaccine Discovery and Design.

Bhullar, Deepika; Nemazee, David.

Curr Top Microbiol Immunol; 428: 165-180, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-30919086

16.

Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles.

Melo, Mariane; Porter, Ely; Zhang, Yuan; Silva, Murillo; Li, Na; Dobosh, Brian; Liguori, Alessia; Skog, Pat; Landais, Elise; Menis, Sergey; Sok, Devin; Nemazee, David; Schief, William R; Weiss, Ron; Irvine, Darrell J.

Mol Ther; 27(12): 2080-2090, 2019 12 04.

Artículo en Inglés | MEDLINE | ID: mdl-31515132

17.

The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8⁺ Thymocyte Selection.

Martinic, Marianne M; Caminschi, Irina; O'Keeffe, Meredith; Thinnes, Therese C; Grumont, Raelene; Gerondakis, Steve; McKay, Dianne B; Nemazee, David; Gavin, Amanda L.

J Immunol; 198(7): 2649-2660, 2017 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-28202617

18.

Generation of T follicular helper cells in vitro: requirement for B-cell receptor cross-linking and cognate B- and T-cell interaction.

Kolenbrander, Anne; Grewe, Bastian; Nemazee, David; Überla, Klaus; Temchura, Vladimir.

Immunology; 153(2): 214-224, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-28881401

19.

Receptor editing in lymphocyte development and central tolerance.

Nemazee, David.

Nat Rev Immunol; 6(10): 728-40, 2006 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-16998507

20.

B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates.

Ota, Takayuki; Doyle-Cooper, Colleen; Cooper, Anthony B; Doores, Katherine J; Aoki-Ota, Miyo; Le, Khoa; Schief, William R; Wyatt, Richard T; Burton, Dennis R; Nemazee, David.

J Immunol; 191(6): 3179-85, 2013 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-23940273

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